一、基本信息
郭韬,男,汉族,中共党员,博士,教授,博士生导师。
二、学习经历
2007年9月-2011年7月,陕西师范大学 生物学基地班专业,获理学学士学位;
2011年9月-2018年6月,中国科学院上海生命科学研究院植物生理生态研究所,遗传学专业,获理学博士学位。
三、工作经历
2018年6月-2022年7月,中国科学院分子植物科学卓越创新中心,博士后;
2022年9月至今,西北农林科技大学 未来农业研究院 教授。
四、研究方向
作物功能基因组学与生物育种
1. 作物产量性状协调发育平衡的分子调控机理
2. 作物复杂性状偶联的分子遗传和表观遗传基础
3. 作物生物育种
五、主持基金
2018.11-2020.10,主持中国博士后科学基金会面上资助项目:小肽-类受体激酶调控水稻粒型和穗型发育的分子机理;
2019.01-2020.12,主持上海市“超级博士后”激励计划项目:水稻穗粒数和粒型协调发育的分子调控机理;
2020.08-2022.07,主持中国博士后科学基金会特别资助(站中)项目:小肽-类受体蛋白激酶信号调控水稻产量性状的分子机理;
2023.01-2025.12,主持国家自然科学基金青年项目:GSN1-MAPK分子模块耦合G蛋白信号调控水稻产量性状形成的分子遗传机理研究。
六、主要学术成果(*共同第一作者,#共同通讯作者)
1. Guo T*, Lu ZQ*, Xiong Y*, Shan JX, Ye WW, Dong NQ, Kan Y, Yang YB, Zhao HY, Yu HX, Guo SQ, Lei JJ, Liao B, Chai J#, Lin HX# (2023) Optimization of rice panicle architecture by specifically suppressing ligand-receptor pairs. Nature Communications 14: 1640.
2. Chen K, Ye C, Guo J, Chen D, Guo T, Liu J, Liu C#, Zhou X# (2023) Agrobacterium-mediated transformation efficiency and grain phenotypes in six indica and japonica rice cultivars. Seed Biology 2: 4.
3. Liu RQ, Ma Y, Guo T#, Li GL# (2023) Identification, biogenesis, function, and mechanism of action of circular RNAs in plants. Plant Communications 4(1): 100430.
4. Zhang H, Zhou JF, Kan Y, Shan JX, Ye WW, Dong NQ, Guo T, Xiang YH, Yang YB, Li YC, Zhao HY, Yu HX, Lu ZQ, Guo SQ, Lei JJ, Liao B, Mu XR, Cao YJ, Yu JJ, Lin Y, Lin HX (2022) A genetic module at one locus in rice protects chloroplasts to enhance thermotolerance. Science 376: 1293-1300.
5. Zhang YM, Yu HX, Ye WW, Shan JX, Dong NQ, Guo T, Kan Y, Xiang YH, Zhang H, Yang YB, Li YC, Zhao HY, Lu ZQ, Guo SQ, Lei JJ, Liao B, Mu XR, Cao YJ, Yu JJ, and Lin HX (2021) A rice QTL GS3.1 regulates grain size through metabolic-flux distribution between flavonoid and lignin metabolons without affecting stress tolerance. Communications Biology 4: 1171.
6. La T*, Chen S*, Guo T, Zhao XH, Teng L, Li DD, Carnell M, Zhang YY, Feng YC, Cole N, Brown A.C, Zhang DD, Dong Q, Wang J.Y, Cao H, Liu T, Thorne R.F, Shao FM#, Zhang XD#, and Jin L# (2021) Visualization of endogenous p27 and Ki67 reveals the importance of a c-Myc-driven metabolic switch in promoting survival of quiescent cancer cells. Theranostics 11(19): 9605-9622.
7. Chen K*, Zhang WT*, La T, Bastains, P.A, Guo T#, and Cao CJ# (2021) Microstructure investigation of plant architecture with X-ray microscopy. Plant Science 311: 110986.
8. Guo T, Lin HX (2021) Creating future crops: a revolution for sustainable agriculture. Journal of Genetics and Genomics 48:97-101.
9. Guo T*, Lu ZQ*, Shan JX, Ye WW, Dong NQ, Lin HX (2020) ERECTA1 acts upstream of the OsMKKK10-OsMKK4-OsMPK6 cascade to control spikelet number by regulating cytokinin metabolism in rice. Plant Cell 32:2763-2779. (2023 ESI Highly Cited Paper)
10. Dong NQ, Sun Y, Guo T, Shi CL, Zhang YM, Kan Y, Xiang YH, Zhang H, Yang YB, Li YC, Zhao HY, Yu HX, Lu ZQ, Wang Y, Ye WW, Shan JX, Lin HX (2020) UDP-glucosyltransferase regulates grain size and abiotic stress tolerance associated with metabolic flux redirection in rice. Nature Communications 11: 2629.
11. Shi CL, Dong NQ, Guo T, Ye WW, Shan JX, Lin HX (2020) A quantitative trait locus GW6 controls rice grain size and yield through the gibberellin pathway. Plant Journal 103: 1174-1188.
12. Guo T*, Chen K*, Dong NQ, Ye WW, Shan JX, Lin HX (2020) Tillering and small grain 1 dominates the tryptophan aminotransferase family required for local auxin biosynthesis in rice. Journal of Integrative Plant Biology 62: 581-600. (Cover Story: Local auxin biosynthesis in rice)
13. Guo T*, Chen HC*, Lu ZQ, Diao M, Chen K, Dong NQ, Shan JX, Ye WW, Huang SJ, Lin HX (2020) A SAC phosphoinositide phosphatase controls rice development via hydrolyzing PI4P and PI(4, 5)P2. Plant Physiology 182: 1346-1358.
14. 郭韬, 余泓, 邱杰, 李家洋, 韩斌, 林鸿宣. 中国水稻遗传学研究进展与分子设计育种. 中国科学: 生命科学, 2019, 49: 1185-1212. (新中国成立70周年生命科学研究进展特邀评述)
15. Chen K, Guo T, Li XM, Yang YB, Dong NQ, Shi CL, Ye WW, Shan JX, Lin HX (2019) NAL8 encodes a prohibitin that contributes to leaf and spikelet development by regulating mitochondria and chloroplasts stability in rice. BMC Plant Biology 19: 395.
16. Chen K*, Guo T*, Li XM*, Zhang YM, Yang YB, Ye WW, Dong NQ, Shi CL, Kan Y, Xiang YH, Zhang H, Li YC, Gao JP, Huang XH, Zhao Q, Han B, Shan JX, Lin HX (2019) Translational regulation of plant response to high temperature by a dual-function tRNAHis guanylyltransferase in rice. Molecular Plant 12: 1123-1142.
17. Guo T, Chen K, Dong NQ, Shi CL, Ye WW, Gao JP, Shan JX, Lin HX (2018) GRAIN SIZE AND NUMBER1 negatively regulates the OsMKKK10-OsMKK4-OsMPK6 cascade to coordinate the trade-off between grain number per panicle and grain size in rice. Plant Cell 30: 871-888. (2023 ESI Highly Cited Paper)
18. Li XM, Chao DY, Wu Y, Huang XH, Chen K, Cui LG, Su L, Ye WW, Chen H, Chen HC, Dong NQ, Guo T, Shi M, Feng Q, Zhang P, Han B, Shan JX, Gao JP, Lin HX (2015) Natural alleles of a proteasome alpha2 subunit gene contribute to thermotolerance and adaptation of African rice. Nature Genetics 47: 827-833.
七、获批专利
1. 林鸿宣,郭韬,单军祥,叶汪薇;控制植物粒数和粒重的GSN1基因、编码蛋白及其应用,专利号:201810196424.8,中国;
2. 林鸿宣,陈可,郭韬,厉新民,单军祥,叶汪薇;AET1-RACK1A-eIF3h复合体在植物环境温度适应性中的应用,专利号:201910059211.5,中国;
3. 林鸿宣,郭韬,单军祥,叶汪薇;调控水稻分蘖数和粒型的新基因TSG1及其应用,专利号:201910334682.2,中国;
4. 林鸿宣,陈可,郭韬,厉新民,单军祥,叶汪薇;控制植物株型、产量等性状的新基因NAL8及其应用,专利号:201910604367.7,中国;
5. 林鸿宣,郭韬,陈华昌,单军祥,叶汪薇;调控水稻穗粒数和株型的新基因GH1及其应用,专利号:201910756064.7,中国;
6. 林鸿宣,郭韬,卢紫琦,单军祥,叶汪薇;ER1-MAPK-DST分子模块及其在植物穗粒数改良中的应用,专利号:202010588759.1,中国。
八、招生学科
生物学(遗传学)
九、联系方式
地址:陕西杨凌西北农林科技大学未来农业研究院
邮编:712100
邮箱:guotao@nwafu.edu.cn